BoltzGen
Generate target-conditioned binder candidates.
Results
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Method & evidence
Generate protein or peptide binder candidates for a target structure and specified epitope residues.
Interpreting results
- A native filter failure is a scientific result for that candidate, not an infrastructure failure.
- Use metrics to prioritize within a consistently configured target campaign; they are not experimental affinities.
References
Input requirements & outputs
Input checks
- One PDB or mmCIF target structure
- Explicit target chain and 1–32 epitope residue numbers
- Protein or peptide protocol with 1–4 designs per run
Expected results
- Candidate cohort — Compare designed sequences, final ranks, native metrics, and filter outcomes.
- Designed complexes — Inspect target–binder mmCIF structures.
- Downloadable results — Designed structures, scores, seeds, and settings.
